Keywords

• Bay 43-9006
• 4-[4-[[4-chloro-3-(trifluoromethyl)phenyl]carbamoylamino]phenoxy]-N-methylpyridine-2-carboxamide,4-methylbenzenesulfonic acid
• Nexavar

Quick Details

• ProName: China Supplier CAS.475207-59-1 High Pu...
• CasNo: 475207-59-1
• Molecular Formula: C28H24ClF3N4O6S
• Appearance: White powder
• Application: medical intermediate
• DeliveryTime: 8-10 working days
• PackAge: 25kg/cartoon box
• Port: Tianjin , shanghai port
• ProductionCapacity: 50000 Kilogram/Month
• Purity: 99%
• Storage: Dry and Clean Place
• Transportation: By air, sea and express
• LimitNum: 1 Kilogram
• Moisture Content: 0.01%
• Impurity: 0.01%
• Brand name: SENYI
• ORIGIN: CHINA
• Chemcial name: Sorafenib Tosylate

Superiority

China Supplier CAS.475207-59-1 High Purity Sorafenib Tosylate

Sorafenib tosylate
475207-59-1

Product Name: Sorafenib tosylate
Synonyms: SORAFENIB TOSYLATE;Sorafenib & its intermediates;Sorafinib mesylate;4-Methyl-3-((4-(3-pyridinyl)-2-pyrimidinyl)amino)-N-(5-(4-methyl-1H-imidazol-1-yl)-3-(trifluoromethyl)phenyl)benzamide monomethanesulfonate;Sorafenib Tosylate(Bay 43-9006,Nexavar);SORAFENIB TOSYLATE (BAY 43-9006 TOSYLATE);BAY 43-9006;BAY43-9006;4-(4-(3-(4-Chloro-3-(trifluoromethyl)phenyl)ureido)phenoxy)-N2-methylpyridine-2-carboxamide mono (4-methylbenzenesulfonate)
CAS: 475207-59-1
MF: C28H24ClF3N4O6S
MW: 637.0265696
EINECS: 641-758-8

General Description:    

Sorafenib is available in 200-mg tablets for oral administrationand is used in the treatment of RCC and colon cancer.The agent is classified as a multikinase inhibitor because ofits action on numerous kinase enzymes including thePDGF-R, Kit, and Raf. Sorafenib is 39% to 48% bioavailable and CYP3A4-mediated metabolism giveseight identified metabolites including the N-oxide, which isequally active with the parent. However, the majority of thedrug in plasma is present as the parent compound.Sorafenib is highly protein bound (99.5%). The drug iseliminated primarily in the feces (77%) with 19% appearingin the urine as glucuronides (UGT1A1) and has a eliminationhalf-life of 24 to 48 hours. The most commonly seentoxicity is skin rash that normally occurs within the first6 weeks of therapy. Other adverse effects include hypertension,fatigue, increased wound healing time, and increasedrisk of bleeding.

Uses: An inhibitor of Flk-1 (VEGFR), PDGFR and Raf kinases.

Details

Our Strengths.

1.High quality with competitive price.

2. All purity>99%.

3. We are manufacturer and can provide high quality products with factory price.

Fast and safe delivery.

1. Parcel can be sent out in 24 hours after payment tracking number available.

2. Secure and discreet shipment verious transportation methods for your choice.

3. Customs pass rate >99%.

4. We have our own agent/remailer/distributor who can help us ship our products very fast and safe, and we have stock in there for transferring.

We have clients throughout the world.

1. Professional service and rich experience make customers feel at ease, adequate stock and fast delivery meet their different desire.

2. Market feedback and goods feedback will be appreciated, meeting customers' requirement is our principal responsibility.

3. High quality, competitive price, fast delivery, first-class service gain the trust and praise from all the customers.

FAQ
1. How is the quality
above 99% purity.

2. How is the package
Foil bag or customers' requirement.

3. How is the storage
Keep dry and cool place.

4. Do I need to pay extra for shipping cost
Our price includes the shipping cost already.

5. Can I order sample for testing
Yes, welcome your sample order before bulk order. We will send the samples directly to your door by express. The quality of sample will prove our ability and our products quality.